Effect of Bright Light Therapy on Motor and Sleep Symptoms in Parkinsons Disease Patients Aged 50 to 80

What this Trial Is About

Researchers are evaluating the effects of bright light therapy on motor symptoms and sleep disorders in patients with Parkinsons disease. This randomized controlled trial aims to clarify how bright light affects these symptoms and explore the possible mechanisms behind these effects. Previous studies have shown benefits of light therapy on sleep quality, mood, anxiety, and motor function in Parkinsons disease, but these findings have not been reported in Chinese patients. Participants will be randomly assigned to one of two groups one group receives bright light therapy with a device emitting 10,000 lux, and the other group receives a placebo device emitting 300 lux. Both groups will use their respective light boxes for one hour twice dailyonce in the morning between 800 and 1100 and once in the afternoon between 1700 and 1900over the course of one month. Participants are instructed to stay awake and move under the light source during treatment. Throughout the study, participants will undergo multiple assessments at baseline and at 4, 8, and 12 weeks to monitor sleep quality through polysomnography and various clinical scales measuring motor and non-motor symptoms of Parkinsons disease. Researchers will also evaluate brain activity, hormone levels, anxiety, depression, cognition, and quality of life. Safety and effects will be closely monitored during these visits, with the total study duration lasting up to 12 weeks.

Light Therapy in Parkinson's Disease