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ID07159334

Comparing Lignocaine and 0.2% Glyceryl Trinitrate Ointments for Pain Relief and Healing After Hemorrhoid Surgery

Led by King Edward Medical University · Updated on 2025-09-08

64

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

This research aims to compare the effectiveness of topical lignocaine ointment versus 0.2% glyceryl trinitrate GTN ointment for reducing postoperative pain and promoting wound healing in patients undergoing hemorrhoidectomy. Hemorrhoids are swollen veins in the anal area, and pain after surgery can delay recovery and affect comfort. The study focuses on determining which ointment provides better pain relief and wound healing outcomes following hemorrhoid removal surgery. Patients undergoing hemorrhoidectomy will be randomly assigned to one of two groups. One group will receive lignocaine ointment applied locally to the anal wound three times daily after surgery, while the other group will receive 0.2% GTN ointment on the same schedule. Both groups will receive standard postoperative care including sitz baths, stool softeners, and paracetamol for pain relief. The study will follow participants for 3 to 6 months overall, with treatment and monitoring focused on the first month after surgery. Participants will have their pain levels assessed using a visual analog scale VAS at various times after surgery, including 6, 12, 24, 48, and 72 hours, as well as at 7, 14, 21, and 28 days. Wound healing time will be tracked up to one month, and patient satisfaction will be measured at 6 weeks using a 5-point scale. Additional monitoring includes recording the time to first analgesic request, analgesia amounts, and any side effects such as wound secretion, itching, bleeding, or headaches. Data will be analyzed to compare outcomes between the two ointments.

CONDITIONS

Brief Title

"Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")

Research Team

H

Hafiz Ahmad Rauf, Mbbs,Fcps

K

KEMU/ Mayo Hospital lahore

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