Comparing Linked-Color Imaging and Indigo Carmine Spray for Detecting Colorectal Adenomas A Randomized Study on Colonoscopy Techniques to Improve Polyp Detection

What this Trial Is About

Researchers are evaluating two methods to improve the detection of colorectal adenomas during colonoscopy, which is important for preventing colorectal cancer. The study compares linked-color imaging LCI, a new endoscopy technology that enhances lesion visibility using optimized colors, with indigo carmine chromoendoscopy, which involves spraying a dye on the colon lining. This prospective, randomized controlled trial aims to explore whether LCI can increase the adenoma detection rate compared to the dye spraying method. Participants who qualify will be randomly assigned to one of two groups after reaching the cecum during colonoscopy. One group will undergo colonoscopy using linked-color imaging to carefully observe the colon during withdrawal. The other group will receive indigo carmine dye spray during withdrawal for lesion detection. Any polyps or lesions found will be removed and examined pathologically. Data such as patient demographics, colonoscopy duration, and lesion details will be collected and analyzed. During the study, participants will undergo colonoscopy with either LCI or indigo carmine spraying, and lesions will be recorded and removed as needed. Researchers will measure the adenoma detection rate as the primary outcome, along with the detection rate of various lesion types. Patient information, colonoscopy data, and lesion characteristics will be documented. Statistical analysis will be conducted to compare outcomes. The study will follow participants from the start of the procedure to lesion assessment, aiming to provide evidence on the clinical value of LCI in colonoscopy.

Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate