Actively Recruiting
Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate
Led by Shandong University · Updated on 2025-05-07
352
Participants Needed
1
Research Sites
51 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate, but considering the long withdrawal time of the endoscope and the resulting increase in time and cost. Linked-color imaging (LCI) is a newly developed image-enhanced endoscopy technology. It relies on wave length optimization of three colors (red, green, and blue) to make the lesions appear fuller. LCI improves the visibility of colorectal adenomas and polyps and may increase the detection rate of lesions. In order to explore the clinical application value of Linked-color imaging endoscopy, we performed a prospective, randomized controlled trial to compare adenoma detection rate of Linked-color imaging endoscopy and indigo carmine chromoendoscopy.
CONDITIONS
Official Title
Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 45 and 85 years
- History of colorectal adenoma
- First-degree relatives with colorectal cancer or colorectal adenoma
- Presence of gastrointestinal symptoms such as abdominal pain, bloody stool, chronic diarrhea or constipation, unexplained anemia, or weight loss
- Positive Fecal Immunochemical Test
You will not qualify if you...
- Pregnancy
- Inflammatory bowel disease
- Familial adenomatosis polyposis
- Suspected colorectal cancer
- Intestinal obstruction
- Coagulopathy
- Use of aspirin, clopidogrel, or other anticoagulants/antiplatelet drugs within 7 days prior to the study
- Previous colorectal resection
- Failed cecal intubation
- Inadequate bowel preparation quality (BBPS ≤5)
- Refusal to participate or provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Qilu Hospital of Shandong University
Jinan, Shandong, China, 250012
Actively Recruiting
Research Team
R
Rui Ji MD PHD
CONTACT
R
Rui Ji MD PHD, +86-18560086103
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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