Study of Cooled and Warmed Sodium Chloride Injections to Treat Lipomas

What this Trial Is About

Lipomas are common benign tumors made of mature fat tissue, often removed for cosmetic reasons or because they press on nearby structures. This research explores subcutaneous injections of cooled normal saline as a possible nonsurgical treatment for lipomas. The study also includes an additional group to assess warmed normal saline injections, aiming to find a more comfortable alternative to fat-freezing devices applied on the skin. Participants will receive injections directly into their lipomas using either cooled or warmed sterile sodium chloride mixed with lidocaine and epinephrine. The volume of the injected solution will be three times the estimated lipoma size. After the injection, the area will be gently massaged to distribute the solution evenly. This study includes multiple treatments spaced about four weeks apart. During the study, researchers will monitor pain and redness fifteen minutes after each injection, as well as changes in lipoma size after multiple treatments and up to twelve weeks following the last injection. Participants may receive up to four treatments, and the study is designed to evaluate safety and effectiveness over this period. The total participation duration varies, with ongoing assessments throughout the treatment and follow-up phases.

Lipomas Treated With Subcutaneous Injections of Cooled or Warmed Sodium Chloride