Actively Recruiting

Phase 3
Age: 18Years - 70Years
All Genders
NCT06430112

Liposomal Bupivacaine vs Ropivacaine for TAPBs

Led by Sun Yat-sen University · Updated on 2024-05-28

74

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Few studies have compared the efficacy of ultrasound (US)-guided TAP blocks with Liposomal bupivacaine(LB) versus ropivacaine in reducing postoperative opioid usage in patients undergoing laparoscopic lower abdominal tumor Resection. Therefore, we are conducting this prospective, randomized controlled trial to compare the postoperative analgesic effects of LB and ropivacaine for TAP blocks among patients undergoing laparoscopic colorectal procedures.

CONDITIONS

Official Title

Liposomal Bupivacaine vs Ropivacaine for TAPBs

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing laparoscopic resection of lower abdominal tumors
  • ASA grade II-III
  • Age 18 to 70 years
Not Eligible

You will not qualify if you...

  • Patient does not agree to participate in the clinical study
  • History of opioid tolerance or allergy
  • History of local anesthetic allergy
  • History of dementia, mental illness, or other central nervous system diseases
  • History of chronic pain or current use of opioids or other analgesics
  • Poor general condition with serious cardiovascular, respiratory, digestive, urinary, or central nervous system diseases with life expectancy less than 3 months
  • History within 12 months before surgery of myocardial infarction, severe or unstable angina, coronary artery bypass grafting, congestive heart failure, cerebrovascular accident, or pulmonary embolism
  • Pregnant women
  • Unable to cooperate with follow-up or poor compliance
  • Acute myocardial infarction, cardiac arrest, or shock during surgery or hospitalization
  • ASA score above grade III

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Jingdun Xie

Guangzhou, Guangdong, China, 510060

Actively Recruiting

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Research Team

P

Ping Yu

CONTACT

J

Jingdun Xie

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Liposomal Bupivacaine vs Ropivacaine for TAPBs | DecenTrialz