Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT07366502

Liposomal vs Conventional Oral Iron After Sleeve Gastrectomy

Led by Medeni Şermet · Updated on 2026-04-13

70

Participants Needed

1

Research Sites

69 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Low-dose liposomal iron (17-34 mg elemental/day) was compared with standard conventional oral iron (100-200mg elemental/day) in the treatment of iron deficiency anemia following sleeve gastrectomy. Liposomal iron provided superior hematological improvement and gastrointestinal tolerance.

CONDITIONS

Official Title

Liposomal vs Conventional Oral Iron After Sleeve Gastrectomy

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • History of laparoscopic sleeve gastrectomy performed at least 6 months prior to enrollment
  • Diagnosis of iron deficiency anemia with hemoglobin less than 12 g/dL in women or less than 13 g/dL in men
  • Serum ferritin less than 30 ng/mL or transferrin saturation (TSAT) less than 20%
  • Mild to moderate anemia with hemoglobin 9 g/dL or higher
  • Ability to take and swallow oral medications
  • Willingness to participate and provide written informed consent
Not Eligible

You will not qualify if you...

  • Active gastrointestinal disease such as inflammatory bowel disease, peptic ulcer disease, or gastrointestinal bleeding
  • Chronic kidney disease with estimated GFR less than 30 mL/min/1.73 m²
  • Use of oral or parenteral iron, vitamin B12, or folate supplements within the previous 3 months
  • Iron overload or hemochromatosis with serum ferritin greater than 300 ng/mL
  • Known allergy or intolerance to iron preparations
  • Active malignancy
  • Pregnancy or breastfeeding
  • Known hemoglobin disorders such as thalassemia or sickle cell disease
  • Blood transfusion within the previous 1 month
  • Cognitive or psychiatric disorders interfering with participation or adherence

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Goztepe Prof.Dr. Suleyyman Yalçın City Hospital

Istanbul, kadıköy, Turkey (Türkiye), 34630

Actively Recruiting

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Research Team

M

Medeni Sermet, assoc.prof

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Liposomal vs Conventional Oral Iron After Sleeve Gastrectomy | DecenTrialz