Actively Recruiting
Liposomal and Standard Bupivacaine in Thoracic Paravertebral Block for Post-Thoracoscopic Pain
Led by Yongtao Sun · Updated on 2026-01-09
496
Participants Needed
1
Research Sites
87 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
I. Research purpose 1.1 Main Objective: To investigate the efficacy and safety of bupivacaine liposome thoracic paravertebral nerve block for postoperative analgesia after thoracoscopic lobectomy 1.2 Exploratory Objective: To investigate the noninferiority of bupivacaine liposomes in thoracic paravertebral nerve block with standard bupivacaine
CONDITIONS
Official Title
Liposomal and Standard Bupivacaine in Thoracic Paravertebral Block for Post-Thoracoscopic Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Undergoing unilateral initial thoracoscopic lobectomy under general anesthesia (thoracoscopic or robot-assisted)
- American Society of Anesthesiologists (ASA) physical status classification I to III
- Willing to voluntarily participate and sign informed consent
You will not qualify if you...
- Pregnant or lactating women
- Pulmonary wedge-shaped resection
- Having two or more thoracic drainage tubes
- Abnormal liver function: ALT and/or AST greater than 2 times upper limit of normal, or total bilirubin greater than 1.5 times upper limit of normal
- Impaired kidney function (serum creatinine over 176 µmol/L) or dialysis within 28 days before surgery
- Participation in another investigational drug trial within the past 6 months
- History of drug or alcohol abuse
- Long-term opioid use (more than 3 months or over 5 mg morphine equivalent daily for 1 month)
- Allergy history to local anesthetics or study drugs
- Uncontrolled mental or neurological symptoms
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Qianfoshan Hospital, The First Hospital affiliated of Shandong First Medical University
Jinan, Shandong, China, 250014
Actively Recruiting
Research Team
Y
yong t Sun, PH.D
CONTACT
J
jian bo Wu, PH.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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