Actively Recruiting

Age: 40Years - 75Years
FEMALE
NCT06249308

Liquid Biopsy-based Early Detection of Ovarian Cancer: a Proof-of-concept Study ( PROFOUND-OC )

Led by Fudan University · Updated on 2024-02-08

168

Participants Needed

3

Research Sites

158 weeks

Total Duration

On this page

Sponsors

F

Fudan University

Lead Sponsor

S

Shanghai Weihe Medical Laboratory Co., Ltd.

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is a multi-center, observational study aiming at developing a machine learning-based early detection model using prospectively collected liquid biopsy samples from newly diagnosed ovarian cancer.

CONDITIONS

Official Title

Liquid Biopsy-based Early Detection of Ovarian Cancer: a Proof-of-concept Study ( PROFOUND-OC )

Who Can Participate

Age: 40Years - 75Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 40 and 75 years
  • Clinically and/or pathologically diagnosed ovarian cancer
  • No prior or ongoing systemic or local antitumor therapy, including surgery, radiochemotherapy, endocrine therapy, targeted therapy, immunotherapy, or interventional therapy
  • Able to provide written informed consent and willing to comply with all study procedures
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • Known prior or current diagnosis of other types of cancer
  • Severe acute infection or febrile illness (body temperature ≥ 38.0 °C) within 14 days before blood draw
  • History of organ, bone marrow, or stem cell transplant
  • Blood transfusion within 30 days before blood draw
  • Received therapy including antibiotics, glucocorticoids, or specific drugs within 14 days before blood draw
  • Any other conditions deemed unsuitable by investigators

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Sun Yat-sen Memorial Hospital

Guangzhou, Guangdong, China, 110042

Not Yet Recruiting

2

Liaoning Cancer Hospital & Institute

Shenyang, Liaoning, China, 110042

Not Yet Recruiting

3

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China, 200032

Actively Recruiting

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Research Team

H

Hao Wen, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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