Actively Recruiting
Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Led by University Health Network, Toronto · Updated on 2025-11-26
2500
Participants Needed
1
Research Sites
465 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this protocol is to develop an institution-wide liquid biopsy protocol that will establish a common process for collecting blood and corresponding archived tumor specimens for future research studies at the University Health Network's Princess Margaret Cancer Centre. Circulating cell-free nucleic acids (cfNA), including cell-free DNA (cfDNA) and cell-free RNA (cfRNA), are non-invasive, real-time biomarkers that can provide diagnostic and prognostic information before cancer diagnosis, during cancer treatment, and at disease progression. Cancer research scientists and clinicians at the Princess Margaret are interested in incorporating the collection of peripheral blood samples ("liquid biopsies") into research protocols as a means of non-invasively assessing tumor progression and response to treatment at multiple time points during a patient's course of disease.
CONDITIONS
Official Title
Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with confirmed solid tumor or blood cancer, OR patients at high risk for cancer based on genetic or family history
- Patients aged 18 years or older
- Signed and dated informed consent form for this study
- If co-consented for another primary research study, must meet that study's eligibility criteria
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Princess Margaret Cancer Centre
Toronto, Ontario, Canada, M5G2M9
Actively Recruiting
Research Team
C
Celeste Yu, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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