Actively Recruiting

Age: 18Years +
All Genders
NCT07303712

Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90

Led by Palo Alto Veterans Institute for Research · Updated on 2025-12-26

12

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to determine if baseline liquid biopsy assays (CTC and cf-DNA) as well as single circulating tumor cell-DNA (sCTC DNA) dynamics in the early post-treatment period can predict subsequent treatment response to Y-90 radioembolization in patients with hepatocellular carcinoma (HCC).

CONDITIONS

Official Title

Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of hepatocellular carcinoma confirmed by imaging, BCLC stage 0, A, B, or C
  • Approval for transarterial Y90 radioembolization by a multidisciplinary tumor board
Not Eligible

You will not qualify if you...

  • Not eligible for Y90 radioembolization procedure
  • Prior surgery or ablation on the tumors planned for Y90 treatment
  • Inability to complete required follow-up visits for clinical care or research

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VA Palo Alto Health Care System

Palo Alto, California, United States, 94304

Actively Recruiting

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Research Team

S

Sirish Kishore, MD

CONTACT

L

Luisa Manfredi, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90 | DecenTrialz