Actively Recruiting

Phase 3
Age: 60Years +
All Genders
NCT06361238

Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery

Led by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Updated on 2024-12-20

260

Participants Needed

1

Research Sites

175 weeks

Total Duration

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AI-Summary

What this Trial Is About

This study aims to clarify the preventive effect of perioperative liraglutide application on postoperative delirium in elderly patients with Type 2 diabetes undergoing cardiac surgery.

CONDITIONS

Official Title

Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 60 years or older
  • Diagnosis of Type 2 diabetes
  • Scheduled for elective cardiac surgery
Not Eligible

You will not qualify if you...

  • History of neurological or psychiatric disorders such as schizophrenia, epilepsy, Parkinson's disease, or severe dementia
  • Severe communication difficulties including visual, auditory, or speech impairments
  • History of central nervous system damage or surgery
  • Cardiac function classified as NYHA Class IV
  • Severe liver dysfunction (Child-Pugh Class C)
  • Severe renal failure requiring renal replacement therapy
  • History of pancreatitis
  • Diagnosis of Type 1 diabetes
  • Blood sugar not controlled within 4-8 mmol/L during screening
  • Medullary thyroid carcinoma or family history of it
  • Pregnant or breastfeeding women
  • Allergy or intolerance to liraglutide
  • Previous use of GLP-1A or SGLT2i medications
  • Refusal to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wenxue liu

Nanjing, Jiangsu, China, 210000

Actively Recruiting

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Research Team

W

Wenxue Liu, PhD,MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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