Actively Recruiting
LIRRH Trial for the Right-sided Colon Cancer
Led by Chaoxi Zhou · Updated on 2025-10-03
120
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this clinical trial is to compare the short- and long-term outcomes of laparoscopic ileocecal reconstruction right hemicolectomy (LIRRH) with those of traditional laparoscopic right hemicolectomy (TRH) for ascending and proximal transverse colon cancer.
CONDITIONS
Official Title
LIRRH Trial for the Right-sided Colon Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-75 years
- ASA physical status �3 III
- Colon adenocarcinoma confirmed by endoscopy and biopsy
- Primary tumor located in ascending colon or proximal transverse colon shown by contrast-enhanced abdominal CT
- Pre-operative clinical stage TanyNanyM0
- Able to understand the study and provide written informed consent
You will not qualify if you...
- History of hypertensive crisis or hypertensive encephalopathy
- Severe cardiopulmonary insufficiency or other surgery contraindications
- Uncorrectable electrolyte imbalances such as potassium, calcium, or magnesium
- Significant bleeding risks including prior intracranial/intraspinal hemorrhage, tumor invading major vessels, recent thrombotic or embolic events, or vascular disease
- Recent clinically relevant hemoptysis or tumor bleeding within 1 month before screening
- Therapeutic-dose anticoagulation within 2 weeks before treatment (except low-molecular-weight heparin)
- Antiplatelet therapy within 10 days before treatment exceeding specified doses
- Active tuberculosis
- Active autoimmune diseases or history with expected recurrence
- Evidence of multiple primary colorectal cancers requiring more bowel resection
- Tumor infiltration into adjacent organs needing multi-visceral resection
- Distant metastasis or unresectable disease
- Other malignancies within past 5 years except certain cured skin or thyroid cancers
- Intestinal obstruction, perforation, or bleeding needing emergency surgery
- Unsuitable or unable to tolerate laparoscopic surgery
- Pregnant or lactating women
- Psychiatric disorders preventing compliance
- Prior neoadjuvant therapy
- Multidisciplinary team decision deeming patient inappropriate
- Unable to understand or refusing informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Fourth Hospital of Hebei Medical University
Shijiazhuang, Hebei, China, 050000
Actively Recruiting
Research Team
C
Chaoxi Zhou, MD
CONTACT
M
Meng Zesong
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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