Comparing Laparoscopic Ileocecal-Sparing and Traditional Right Hemicolectomy for Hepatic Flexure and Proximal Transverse Colon Cancer in a Randomized Trial

What this Trial Is About

Researchers are comparing two surgical methods for treating cancer in the hepatic flexure and proximal transverse colon Laparoscopic Ileocecal-Sparing Right Hemicolectomy LISH and traditional laparoscopic right hemicolectomy TRH. This prospective, multicenter, open-label, randomized clinical trial aims to evaluate long-term outcomes such as disease-free survival, overall survival, and quality of life after these surgeries. Participants are randomly assigned to either the LISH group, where a novel surgery preserving the ileocecal region is performed, or the TRH group, undergoing the standard right hemicolectomy. Both procedures involve precise dissection of lymph nodes and colon resection with different surgical techniques and anastomosis types. The study monitors outcomes over several years, including perioperative complications and colonoscopy findings of new polyps or adenomas. During the study, patients will be evaluated for surgical complications within 30 days, the quality of surgical specimens, and quality of life through specific rating scales over three years. Follow-up includes colonoscopies to detect new growths and monitoring of overall survival for up to five years. This extended monitoring helps researchers understand the long-term effects and benefits of the two surgical approaches.

LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer