Actively Recruiting

Phase 4
Age: 18Years - 70Years
All Genders
NCT06184581

Lithium Versus Lamotrigine in Bipolar Disorder, Type II

Led by University Hospital Bispebjerg and Frederiksberg · Updated on 2026-03-20

200

Participants Needed

1

Research Sites

186 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The investigators want in a 6-month randomized controlled trial (RCT) to compare effects of lithium versus lamotrigine on mood stabilization and other critical patient outcomes in patients with BDII.

CONDITIONS

Official Title

Lithium Versus Lamotrigine in Bipolar Disorder, Type II

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Bipolar Disorder, type II confirmed by SCAN interview
  • Age between 18 and 70 years
  • Able to give informed consent
Not Eligible

You will not qualify if you...

  • Past non-response or intolerance to lamotrigine or lithium after more than 6 weeks of proper treatment
  • Currently taking mood stabilizers at enrollment
  • Severe chronic kidney disease
  • Severe cardiac insufficiency
  • Brugada syndrome
  • Severe hypothyroidism not controlled by treatment
  • Women who are pregnant, breastfeeding, or planning pregnancy soon

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Psychiatric Center Copenhagen

Copenhagen, Denmark

Actively Recruiting

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Research Team

L

Lars Vedel Kessing, professor, MD, DMSc.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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