Actively Recruiting
Liver Cancer Disparities in American Indian and Alaska Native Persons
Led by University of Washington · Updated on 2024-06-04
200
Participants Needed
1
Research Sites
230 weeks
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
We are performing a pilot and feasibility randomized controlled trial (RCT) of HCC screening by US + AFP every 6 months (n=100), the current standard-of-care, versus aMRI + AFP every 6 months (n=100) for 12 months (i.e. at time 0, 6 and 12 months) among AI/AN patients with cirrhosis or HBV.
CONDITIONS
Official Title
Liver Cancer Disparities in American Indian and Alaska Native Persons
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Cirrhosis from any cause or chronic hepatitis B infection
- High risk of hepatocellular carcinoma
- Age between 18 and 75 years
- Able to provide informed consent
You will not qualify if you...
- Prior diagnosis of hepatocellular carcinoma
- Current suspicion of hepatocellular carcinoma
- Previous organ transplantation
- Participation in another liver cancer screening trial
- Child-Turcotte-Pugh (CTP) score of 10 or higher
- MELD-Na score greater than 20
- Glomerular filtration rate (GFR) less than 30
- Life expectancy less than 5 years
- Contraindications to MRI
- Unable to complete study visits
- Currently pregnant
AI-Screening
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Trial Site Locations
Total: 1 location
1
Cherokee Nation Health Service
Tahlequah, Oklahoma, United States, 74464
Actively Recruiting
Research Team
J
Jennifer R Harry
CONTACT
S
Stephanie Y Park
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
2
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