Actively Recruiting

Phase Not Applicable
Age: 8Years - 17Years
All Genders
Healthy Volunteers
NCT05395767

LIVing Donor Allograft for Anterior Cruciate Ligament Reconstruction Study

Led by Maidstone & Tunbridge Wells NHS Trust · Updated on 2025-05-23

40

Participants Needed

1

Research Sites

363 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The Anterior Cruciate Ligament (ACL) is a major stabiliser of the knee. ACL rupture is being increasingly identified in children and skeletally immature patients. The current advice in younger patients is usually to undergo ACL reconstruction. The choice of an ideal graft in children is difficult This study will use a technique involves the use of hamstring tendons from a living donor, where the adult (usually a parent) agrees to donate their hamstring tendons, which are dissected out of them and implanted into the child

CONDITIONS

Official Title

LIVing Donor Allograft for Anterior Cruciate Ligament Reconstruction Study

Who Can Participate

Age: 8Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 8 to 17 years inclusive with confirmed ACL rupture requiring reconstruction
  • Patients who have had previous meniscal surgery
  • Patients with current meniscal problems
  • Child and responsible adult agree to use living donor allograft for ACL reconstruction
  • Donor has not had previous tendon harvest on the chosen donor limb
  • Patients willing to attend follow-up visits and complete knee questionnaires and ligament testing
Not Eligible

You will not qualify if you...

  • Previous ACL surgery on the same limb requiring revision
  • Immunosuppressed patients or those on immunosuppressive therapy
  • Unable to attend follow-up appointments
  • Donors who have had hamstring tendon surgery on the donor limb
  • Positive blood tests for transmissible infections in patients or donors
  • Donors at risk of transmissible infection per questionnaire
  • Donors not healthy enough for tenotomy under general anesthesia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Trauma & Orthopaedic Dept, Tunbridge Wells Hospital

Pembury, Kent, United Kingdom, TN2 4QJ

Actively Recruiting

Loading map...

Research Team

H

Helen Sankey, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here