Actively Recruiting
Living Well With Lymphoma
Led by University of Michigan Rogel Cancer Center · Updated on 2025-10-30
100
Participants Needed
1
Research Sites
234 weeks
Total Duration
On this page
Sponsors
U
University of Michigan Rogel Cancer Center
Lead Sponsor
A
American Institute for Cancer Research
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this study the investigators are proposing to evaluate the efficacy, sustainability, and mechanisms of 3 months of individualized counseling of the FRD delivered by registered dietitians, over 8 sessions by phone/video conferencing on fatigue, quality of life, and associated symptoms in persistently fatigued lymphoma cancer survivors compared to 3 months of individualized counseling of the attention control (matched for time and frequency of interactions with the FRD) the General Health Curriculum (GHC). The investigators will randomize and follow 68 lymphoma cancer survivors; accounting for a \~10% drop out rate to achieve a target of 60 patients that will complete the study. The investigators hypothesize that persistently fatigued lymphoma cancer survivors will experience improvements in fatigue, quality of life, and symptoms commonly associated with fatigue, which are then maintained at 15-months post-enrollment; and decreased CRP and alterations in inflammation-associated DNA methylation consistent with reduced inflammation from following the FRD as compared to the GHC.
CONDITIONS
Official Title
Living Well With Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women and men aged 18 years and older
- Diagnosis of lymphoma (Hodgkin and non-Hodgkin)
- Persistent fatigue with an average score of 4 or higher on the Brief Fatigue Inventory
- Fatigue attributed to lymphoma diagnosis
- Fatigue onset between 12 months before diagnosis and any time after diagnosis
- Fatigue not attributed to other diseases
- Fruit and vegetable intake of 5.5 servings or less per day
- Have or be willing to create an email address to receive study questionnaires electronically
You will not qualify if you...
- Medically unstable condition
- Body mass index below 18.5 kg/m2
- Current untreated mood disorder, such as bipolar or major depressive disorder
- Current untreated anemia
- Current untreated hypothyroidism
- Any initiation, cessation, or change of treatment for chronic medications, dietary supplements, behavioral therapy, physical therapy, or planned changes during the study
- Current diagnosis of cachexia
- Planning pregnancy, currently pregnant, or lactating
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
Research Team
S
Sara Snyder
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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