Actively Recruiting
Localizing Epileptic Networks Using MRI and iEEG
Led by University of Pennsylvania · Updated on 2026-02-13
290
Participants Needed
1
Research Sites
312 weeks
Total Duration
On this page
Sponsors
U
University of Pennsylvania
Lead Sponsor
M
Medical University of South Carolina
Collaborating Sponsor
AI-Summary
What this Trial Is About
Upon successful completion of this study, the investigators expect the study's contribution to be the development of noninvasive imaging biomarkers to predict IEEG functional dynamics and epilepsy surgical outcomes. Findings from the present study may inform current and new therapies to map and alter seizure spread, and pave the way for less invasive, better- targeted, patient-specific interventions with improved surgical outcomes. This research is relevant to public health because over 20 million people worldwide suffer from focal drug-resistant epilepsy and are potential candidates for cure with epilepsy surgical interventions.
CONDITIONS
Official Title
Localizing Epileptic Networks Using MRI and iEEG
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with medication-refractory epilepsy
- Planned intracranial EEG placement
- Hypothesized to have temporal lobe epilepsy
You will not qualify if you...
- Contraindication to 3T MRI such as metal implants or claustrophobia
- Clinical features precluding use of intracranial EEG, including pregnancy
- Prior intracranial surgery or device
- Intracranial EEG findings that are non-diagnostic, such as unidentified seizure onset zones
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
K
Kathryn A Davis, MD, MSTR
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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