Waurn Ponds

This research aims to evaluate the safety and tolerability of two new artificial tear formulations in adults with moderate dry eye disease. The study includes participants who experience dry eye symptoms and already use artificial tears. It is designed to better understand how these new eye lubricants are tolerated and their safety profile. Participants will receive two investigational eye drop products, one drop per eye of each formulation, in a cross-over design following a randomization schedule. Each participant will use both products during the study period. The total participation will last about 21 days, during which the effects of the two artificial tear formulations will be compared. Throughout the study, participants will attend visits including a screening and exit visit scheduled based on observed visit windows. Researchers will monitor the number of treatment-emergent adverse events, assess eye health through biomicroscopy, and measure best corrected visual acuity. These evaluations will take place from screening through the exit visit to ensure safety and tolerability of the treatments.

Researchers are conducting a global, multi-center, prospective post-market study to observe the long-term effectiveness of Boston Scientific neurostimulation systems in managing pain. The study aims to gather real-world clinical outcomes, economic value, and technical performance data of these commercially approved neurostimulation devices when used in routine clinical practice. The treatment involves an initial trial period using a Boston Scientific neurostimulation device for pain relief. Participants who experience a positive response during the trial may proceed to receive a permanent implant of the neurostimulation system. The therapy is tailored individually based on the investigator's judgment and standard care practices at each study site, following specific inclusion and exclusion criteria. Participants will be monitored throughout the trial and permanent implant phases to assess pain relief and overall treatment effectiveness. Assessments may include patient evaluations of pain and ability to complete study requirements. The study focuses on capturing comprehensive data to evaluate both clinical outcomes and device performance during regular use. Total participation duration depends on individual treatment progression from trial to permanent implant.