Grobming

Stroke is a leading cause of physical disability and often results in moderate to severe impairments affecting mobility and daily activities. This research aims to evaluate whether combining robotic-assisted gait training RAGT using the Lokomat device with a novel vibratory stimulation device called Vibramoov can improve walking patterns better than Lokomat training alone. The study focuses on patients undergoing neurological inpatient rehabilitation after stroke to assess changes in gait quality and quantity. Participants will be randomly assigned to one of two groups one receiving Lokomat training combined with Vibramoovs targeted vibratory stimuli, and the other receiving Lokomat training alone. Both groups will undergo a four-week inpatient rehabilitation program during which the amount and schedule of RAGT will be the same. Vibramoov is designed to stimulate muscle-tendon proprioceptors to potentially enhance brain sensorimotor activation and movement execution during walking. During the study, researchers will measure outcomes such as the 6-Minute Walk Test and spatiotemporal gait parameters before and after the intervention. Additional evaluations include functional scores, patient-reported outcomes, blood biomarkers like Brain Derived Neurotrophic Factor, and routine lab tests. A follow-up telephone assessment will take place six months after rehabilitation to assess quality of life and mental health. Statistical analyses will compare the effects of both treatments on walking ability and function.