Search Bar & Filters
Found 1 Actively Recruiting clinical trials
Actively Recruiting
This research investigates how dietary habits and probiotics affect chronic pelvic pain in women who have both endometriosis and irritable bowel syndrome (IBS). Endometriosis is a chronic inflammatory condition affecting hormones and immune responses, often causing abdominal pain and bowel changes. Women with endometriosis are 2 to 3 times more likely to develop IBS, a disorder involving gut-brain interaction and inflammation, which shares similar symptoms to intestinal endometriosis, complicating diagnosis and treatment. The study aims to explore non-drug treatments and enhance understanding of these overlapping conditions. Participants will be divided into three groups: one receiving specific dietary guidance with a low-FODMAP diet plus a placebo, another receiving the same diet combined with probiotics (Lactobacillus species), and a control group continuing their usual diet. The treatment period lasts 12 weeks, after which the improvement in pelvic pain will be assessed. This design is randomized and double-blind to ensure unbiased results. During the study, women will undergo evaluations for pelvic pain improvement at 12 weeks. Researchers will monitor dietary adherence, use of probiotics or placebo, and clinical responses. The primary measure is pain improvement over 12 weeks. Safety and eligibility screening include medical histories and various health assessments. Participants are women aged 18 to 50 who consent to the trial and agree to avoid other treatments during the study period.