Parintins

Researchers are evaluating the effects of isometric handgrip training on ambulatory blood pressure in patients with hypertension. This multi-center study involves medicated patients of both sexes, aged 18 and older, who have controlled hypertension but are not at high cardiovascular risk. The purpose is to determine if this type of training can reduce ambulatory blood pressure, which is a better indicator of cardiovascular risk than clinical blood pressure measurements. Participants will be randomly assigned to one of two groups. The isometric handgrip training group will perform supervised handgrip exercises three times per week for 24 weeks, consisting of four sets of 2-minute isometric contractions at 30% of their maximum grip strength, alternating hands. The control group will perform stretching and relaxation exercises with the same frequency and duration. Both groups will train for a total of 16 minutes per session, with rest periods included. Participants will be evaluated at baseline, after 12 weeks, and after 24 weeks. Researchers will measure changes in ambulatory systolic, diastolic, and mean blood pressure as the primary outcomes. Secondary outcomes include clinical blood pressure and cardiac autonomic modulation. Adherence to the exercise program will be monitored, and any changes in medication or health status will be recorded throughout the study.