Ba Yin Guo Leng Meng Gu Zi Zhi Zhou

This research evaluates the detection rates of colorectal adenomas using two different colonoscopy techniques: enhanced white light imaging (E-WLI) and conventional white light imaging (WLI). The study specifically compares adenoma detection rates, sessile serrated lesion detection rates, total polyp detection rates, and advanced adenoma detection rates. It also examines the characteristics of polyps observed with both imaging methods, including their size and location. Participants are randomly assigned to undergo colonoscopy using either the E-WLI or the WLI technique during both insertion and withdrawal phases. Colonoscopies are performed by experienced specialists using endoscopes equipped with "Xiaohua Tanying" technology. Bowel preparation is assessed before the procedure, and all detected polyps are observed with both imaging modes, documented, and removed or biopsied as necessary. The procedures include careful timing and photographic documentation to ensure thorough examination. Throughout the study, participants undergo standard monitoring and management, including anesthesia and assessment of bowel preparation quality. Data collected include polyp details, procedure times, and pathology results. The primary outcome measured is the adenoma detection rate within 14 days post-procedure. The study includes adults aged 45 to 85 undergoing colonoscopy for screening, positive fecal tests, gastrointestinal symptoms, or follow-up after polyp treatment, with ongoing safety and effectiveness assessments during the trial.