Search Bar & Filters
Found 2 Actively Recruiting clinical trials
Actively Recruiting
Researchers are evaluating and comparing the clinical performance and oral health-related quality of life of complete dentures made by two additive manufacturing workflowsdigital and hybridin adults with complete tooth loss attending a dental clinic in Ecuador. This prospective randomized crossover trial aims to assess denture success, patient quality of life, and the relationship between chewing force and denture wear. The study includes adults aged 50 to 90 who require bimaxillary complete dentures. Participants receive two sets of dentures in random order one made entirely through digital workflow involving intraoral scanning, CAD design, and 3D printing in three appointments the other made through a hybrid workflow combining conventional impressions, digitization, CAD, and 3D printing in five appointments. Each denture set is worn for two months without a washout period before crossing over to the other set. After the crossover phase about four months, participants are followed for an additional 12 months to monitor denture wear. During the study, participants undergo assessments including oral health quality of life questionnaires OHIP-EDENT at denture insertion and after two months of wear for each set, clinical evaluations of denture success, measurements of maximum chewing force using a digital occlusal analysis system, and 3D scans to monitor denture wear over time. The total participation time per person is approximately 16 months, with monitoring continuing 12 months after insertion of the second denture set to evaluate long-term outcomes.
Actively Recruiting
Healthy Volunteer
Gingival recessions, which involve the exposure of the root surface due to the downward movement of the gum margin, affect both younger and older adults. This condition can result from anatomical, pathological factors, or trauma, leading to a loss of attachment. Researchers are evaluating the effectiveness of a modified free gingival graft technique to improve treatment outcomes for this condition. The study compares two treatments the modified free gingival graft technique and the conventional free gingival graft method. These surgical procedures aim to increase the height of the keratinized tissue and thicken the gum tissue to support better oral hygiene. Participants will be randomly assigned to one of these treatment groups and receive mucogingival surgery. Participants will be monitored from enrollment through 12 months, with evaluations at 7 and 14 days, one month, and then every three months. Researchers will assess the long-term success of the modified graft technique by measuring root coverage over time. The study includes plaque control assessments and involves regular follow-up visits to track healing and treatment effectiveness.