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Found 2 Actively Recruiting clinical trials

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Actively Recruiting

The trial investigates the use of oxygenated gel compared to Triamcinolone acetonide gel for treating patients with chronic aphthous stomatitis, a condition that causes painful oral ulcers. It is a randomized, double-blind clinical trial conducted by the British University In Egypt to evaluate the effectiveness of these topical treatments in managing aphthous ulcers. Participants are divided into two groups. One group applies 1-2 ml of oxygenated gel directly to the ulcer twice daily for seven days, with training provided on how to apply the gel. The other group uses Triamcinolone acetonide 0.1% oral paste four times daily at set times 8 am, 12 noon, 4 pm, and 8 pm for seven days. Both groups are reexamined at intervals on days 3, 5, 7, and 10 after starting treatment. During the study, participants will have their pain intensity, ulcer size, and healing progress monitored over ten days. Additional assessments include the Oral Health Impact Profile OHIP-14 questionnaire to capture the impact on quality of life. This approach allows researchers to compare the safety and efficacy of the two topical treatments in managing oral aphthous ulcers.

All GendersPhase 2Phase 3
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Actively Recruiting

Healthy Volunteer

Researchers are evaluating the relationship between soft tissue volume and tomographic alveolar ridge classes to improve the classification system for dental implant treatment. This study addresses the current lack of soft tissue components in alveolar ridge topography classifications, which are important for periodontal, restorative, implant, and orthodontic treatments. The goal is to incorporate soft tissue volumetric evaluation into the classification system. Participants will receive oral hygiene instructions and dental cleaning if needed. Digital photographs, intraoral scans, and CBCT scans will be taken as part of the dental implant treatment protocol. A dentist will measure clinical parameters such as gingival biotype, probing depth, gingival thickness, and gingival width. After data collection, a customized treatment plan and dental implant treatment will be completed for each patient. During the study, participants will undergo imaging and clinical assessments to measure soft tissue volume and alveolar ridge classes. Researchers will track the relationship between these measurements over three months as the primary outcome. The study involves comprehensive dental evaluation and treatment planning, including oral hygiene monitoring and clinical parameter evaluation to ensure accurate data collection and treatment.

Age: 18Years +All Genders
1 location