+1 877 705 191424 / 7
HIPAA Compliant
ISO 27001 Certified

Search Bar & Filters

Found 3 Actively Recruiting clinical trials

C

Actively Recruiting

Healthy Volunteer

Researchers are evaluating the clinical and radiographic effects of a new premixed Bioactive bioceramic MTA called Neo-Putty compared to Formocresol in vital pulpotomy treatments of primary molars in children aged 4 to 9 years. This randomized clinical trial aims to determine if Neo-Putty offers better clinical success and fewer adverse effects, addressing concerns about toxic reactions and tissue damage associated with Formocresol. The trial involves two groups one receiving Formocresol applied with a cotton pellet on the amputated pulp for 5 minutes followed by coverage with an intermediate restorative material IRM, and the other treated with Neo-Putty placed directly on the pulp stumps after coronal pulp removal and hemostasis, then covered with reinforced Zinc Oxide-Eugenol IRM. Treatments are given in a single procedure, with the trial designed as a randomized, parallel group, single-blinded study. Participants will be monitored over 12 months with clinical and radiographic evaluations at 3, 6, 9, and 12 months to assess treatment success, including symptom-free status and absence of pulp degeneration signs such as pain, bleeding, root resorption, and bone destruction. The study involves regular follow-up visits to observe healing and detect any complications, supporting improved pediatric dental care practices.

Age: 4Years - 9YearsAll GendersPhase Not Applicable
1 location
C

Actively Recruiting

Healthy Volunteer

Researchers are evaluating different approaches to restore endodontically treated mandibular first permanent molars, focusing on digital, conventional, and biomimetic techniques. The study aims to compare the clinical success, radiographic outcomes, and patient satisfaction of these methods in patients aged 15 years and older. Biomimetic dentistry uses advanced materials to mimic natural tooth function, potentially preserving more tooth structure and enhancing restoration durability. The trial compares three types of restorations EverX Posterior with Vita Endo-Crowns, EverX Posterior with Bulk-Fill Resin Restorations, and Lithium Disilicate Endo-Crowns. These restorations use modern materials and CADCAM technology to simplify preparation and placement, often in a single visit. Biomimetic restorations focus on fiber-reinforced composites to strengthen bonding and evenly distribute chewing forces, aiming to reduce tooth stress and improve longevity. Participants will be reviewed over a 12-month period with clinical exams at 3, 6, 9, and 12 months. Researchers will assess restoration success using visual and tactile tools, radiographs to detect defects or infections, and patient questionnaires about satisfaction with shape, shade, chewing, and flossing ability. Data will be securely stored and analyzed to understand treatment outcomes, with safety and restoration durability monitored throughout the study.

Age: 15Years +All GendersPhase Not Applicable
2 locations
S

Actively Recruiting

This research aims to evaluate the effects of combining resistance exercise training and a high-protein diet on frailty in elderly obese women diagnosed with sarcopenia. The study will recruit sixty women aged 60 to 70 years who meet specific sarcopenia criteria, focusing on improving muscle strength and overall health. Participants will be randomly assigned to different groups to assess the combined impact of exercise and nutrition on their condition. Participants in Group A will engage in supervised resistance exercise sessions three times weekly for 12 weeks, starting with warming up, followed by various strength exercises like leg press and chest press with gradual increases in intensity and duration. They will also follow a high-protein diet providing 1.3 grams of protein per kilogram of body weight daily, spread evenly across meals, with dietary intake monitored biweekly. Group B will receive the same high-protein diet and general health advice but will maintain their usual lifestyle without structured exercise during the study period they will be offered the exercise program after the trial. Throughout the 12 weeks, participants will be monitored through assessments including balance testing, handgrip strength, muscle quality, body measurements like waist-to-hip ratio and body mass index, and quality of life evaluations. Exercise attendance and dietary adherence will be tracked through training logs and dietary records. The studys primary goal is to observe balance improvements, with other health and muscle-related measures as secondary outcomes, to understand how combined exercise and diet interventions affect frailty in this population.

Age: 60Years - 70YearsFEMALEPhase Not Applicable
1 location