Arcachon

There is a wide variation in how rapid sequence induction is performed in operating rooms worldwide. This study aims to describe how French anesthesiologists prevent serious blood flow problems during rapid sequence anesthetic induction in adult patients. It focuses on the occurrence of major hemodynamic disorders, such as low or high blood pressure, sustained arrhythmias, or cardiac arrest within the first 10 minutes after anesthesia begins. Participants will undergo rapid sequence anesthetic induction, a process used to quickly induce general anesthesia for patients at high risk of lung fluid aspiration. The study will observe the clinical practices of pre-oxygenation, induction, and intubation, and check how well these practices follow the formal expert recommendations from 2017 and 2018. Data on the prevention of gastric fluid inhalation, equipment used, drugs administered, and clinical parameters will be collected during the induction process. Throughout the study, researchers will monitor neurological and cardio-respiratory signs and record any complications within the first 10 minutes after anesthesia induction. The main outcome measured is the occurrence of major hemodynamic disorders during this period. The study is observational and multicenter, involving adult patients undergoing rapid sequence induction in France.

The trial investigates the use of cerclage wiring, a common method to support healing in long bone fractures, especially in the femur or humerus. As more people receive hip and shoulder prostheses, fractures around these implants are increasing, mainly in older adults. The study compares a new polymer cerclage system called OrthoLoop with the standard metallic cerclage systems used in current medical care, aiming to assess their effect on fracture healing and bone consolidation over time. Participants will be placed into one of two groups: one receiving the OrthoLoop polymer cerclage and the other receiving the standard metallic cerclage used in routine practice. Both groups undergo surgical implantation of their assigned cerclage system, followed by a 36-month follow-up period. During this time, patients will have consultations and assessments at 6-8 weeks, 3 months, 6 months, and 36 months after surgery to monitor healing and recovery. Throughout the study, researchers will measure how well the fractures consolidate six months after surgery, comparing the polymer cerclage to standard care. Patients will be evaluated using clinical visits where outcomes such as bone healing, possible complications, and overall function will be recorded. The study also tracks any side effects and long-term results for three years to better understand the safety and effectiveness of the polymer cerclage system.