Blendecques

Researchers are evaluating the safety and quality of outpatient care compared to conventional hospital care for patients with acute uncomplicated appendicitis who undergo laparoscopic appendectomy. The study focuses on whether same-day discharge is as safe and effective as staying overnight in the hospital. This approach aims to improve patient satisfaction, reduce hospital stays, lower healthcare costs, and limit exposure risks during situations like the COVID-19 pandemic. The trial compares two treatments: ambulatory appendectomy, where the surgery is done in an outpatient unit and patients leave the hospital the same day, and conventional appendectomy, where patients stay overnight under observation after surgery in a digestive surgery department. Patients included are those with confirmed uncomplicated appendicitis and meet specific health and monitoring criteria, such as having a relative available for monitoring after discharge and living close to a hospital. Participants will be followed for 30 days after surgery to monitor overall safety and recovery. Researchers will assess complications, health status, and any morbi-mortality events during this period. The study includes careful screening before surgery, ongoing safety monitoring, and uses imaging and laboratory tests to confirm eligibility and health status. The total participation period covers the surgery day and 30 days of postoperative follow-up.

The trial investigates the use of cerclage wiring, a common method to support healing in long bone fractures, especially in the femur or humerus. As more people receive hip and shoulder prostheses, fractures around these implants are increasing, mainly in older adults. The study compares a new polymer cerclage system called OrthoLoop with the standard metallic cerclage systems used in current medical care, aiming to assess their effect on fracture healing and bone consolidation over time. Participants will be placed into one of two groups: one receiving the OrthoLoop polymer cerclage and the other receiving the standard metallic cerclage used in routine practice. Both groups undergo surgical implantation of their assigned cerclage system, followed by a 36-month follow-up period. During this time, patients will have consultations and assessments at 6-8 weeks, 3 months, 6 months, and 36 months after surgery to monitor healing and recovery. Throughout the study, researchers will measure how well the fractures consolidate six months after surgery, comparing the polymer cerclage to standard care. Patients will be evaluated using clinical visits where outcomes such as bone healing, possible complications, and overall function will be recorded. The study also tracks any side effects and long-term results for three years to better understand the safety and effectiveness of the polymer cerclage system.