Blendecques

Obesity is a major public health issue in France, especially in the Hauts-de-France region where over 20% of adults are affected. This trial evaluates the effects of adding dramatherapy to a standardized adapted physical activity APA program for adults with obesity enrolled in medical or bariatric care pathways. The study aims to improve emotional expression, body image, self-confidence, psychosocial well-being, and long-term adherence to care through this combination. Participants are randomized to receive either the standard APA program alone or APA combined with dramatherapy. The APA program involves 12 supervised sessions over 6 weeks, including cardiovascular exercises, muscle strengthening, and movement activities suited to patients with obesity. The dramatherapy intervention consists of six weekly group sessions with theatrical expression, role play, improvisation, breathing exercises, and body-oriented creative activities led by a qualified therapist. During the study, participants undergo assessments at baseline, at the end of the 6-week intervention, and at 6- and 12-month follow-ups. These evaluations include quality of life, eating behaviors, body image, self-efficacy, anxiety, depression, adherence to the APA program, and anthropometric measures such as body mass index and body composition. A qualitative component explores patient experiences using interviews and body mapping. The total participation time is about 12 months post-intervention.

Researchers are studying the potential benefits of outpatient care for patients with acute uncomplicated appendicitis treated by laparoscopic appendectomy. This research aims to compare outpatient care with conventional hospital care to see if outpatient care is not worse in terms of overall morbidity and mortality within 30 days after surgery. The study is motivated by the need to optimize care pathways, reduce hospital stays, improve patient satisfaction, and lower healthcare costs, especially important during the COVID-19 pandemic. The trial compares two treatment groups one receiving ambulatory appendectomy where surgery is done in an outpatient surgery unit and patients are discharged the same day, and the other receiving conventional appendectomy where surgery occurs in the digestive surgery department and patients stay overnight for observation before discharge. The study evaluates outcomes up to 30 days after surgery, including hospital stay length, rehospitalization rates, complications, re-interventions, patient satisfaction, quality of life, and economic impacts. Participants will undergo assessments before and after surgery, with monitoring of clinical outcomes, patient satisfaction, and quality of life at 7 and 30 days post-operation. Researchers will also track safety, the rate of conversion from outpatient to conventional care, and costs associated with each care pathway. The total study participation includes follow-up for 30 days after surgery to assess the main and secondary outcomes.

Researchers are investigating the use of a new polymer cerclage system called OrthoLoop in managing fractures of the femur and humerus bones, including those around prosthetic hips and shoulders. This study compares OrthoLoop to standard cerclage systems, mainly metallic ones, to see if it improves bone healing and reduces complications. The study focuses on adults aged 18 and older who require cerclage wiring as part of their fracture treatment. Participants receive either the OrthoLoop polymer cerclage device or a standard cerclage system after surgical repair of their fracture. The study is designed with two groups and follows patients for 36 months after surgery. Follow-up visits are scheduled at 6-8 weeks, 3 months, 6 months, and 36 months to monitor healing, pain, device performance, and any complications. During the study, researchers evaluate bone healing success six months after surgery, track the rate and timing of bone union, and observe any rupture or movement of the cerclage devices. Pain levels and surgical details are recorded at multiple intervals. The study also collects data on complications and surgeon satisfaction with the devices. This thorough follow-up aims to provide a detailed assessment of the OrthoLoop system compared to standard care over three years.