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Found 2 Actively Recruiting clinical trials
Actively Recruiting
Healthy Volunteer
Researchers are comparing two methods for the second reading of screening mammograms in women aged 50 to 74 as part of a breast cancer screening program. The study aims to determine if the AI-assisted reading process is not worse than the standard radiologist reading and if it may be more cost-effective. It focuses on mammograms deemed normal or showing benign lesions from the first reading. Participants mammograms undergo two review paths the standard second reading by a certified radiologist, and an AI-assisted reading where mammograms flagged as suspicious by the AI are then reviewed by a radiologist. The final decision is based on the more concerning assessment from either method. Women will be recalled for further exams if either reading indicates suspicion. During the study, participants receive screening mammograms and their results are monitored for recall rate, cancer detection, sensitivity, specificity, economic impact, time to results, and reading time. The study will follow up for up to 48 months to measure these outcomes. Participants must consent and meet eligibility requirements related to health, imaging quality, and availability for the study duration.
Actively Recruiting
Nasal obstruction NO affects about 30% of people and is a common reason for ear, nose, and throat consultations. It is mainly caused by inflammation such as allergic rhinitis and chronic rhinosinusitis, but can also result from structural issues like septal deviation and inferior turbinate hypertrophy. NO impacts quality of life and smell and contributes to conditions like asthma and sleep apnea. Various questionnaires and tests help assess its impact and severity. This research evaluates the use of anterior active rhinomanometry AAR, a non-invasive method measuring nasal airway resistance, to guide surgical decisions in adults with nasal obstruction. Patients scheduled for surgery, including septoplasty, turbinoplasty, or rhinoplasty, undergo preoperative AAR without nasal decongestants. The study aims to determine if abnormal AAR results can reliably confirm the need for surgery and to compare AAR findings with quality of life scores before and after surgery. Participants will be assessed with AAR and quality of life questionnaires before surgery and followed for three months afterward. Researchers will measure changes in nasal obstruction scores, AAR results, and sleep apnea indicators like the apnea-hypopnea index and CPAP adherence. The study involves preoperative evaluation on the day of surgery and follow-up visits including questionnaires and tests three months postoperatively to monitor improvements and treatment effects.