Draguignan

Researchers are evaluating the use of an AI-assisted method for the second reading of screening mammograms compared to the standard second reading by radiologists. This study aims to determine if the AI-assisted approach is not worse than the standard method and if it offers economic advantages. Participants are women undergoing mammograms as part of the breast cancer screening program in France. The study involves two reading pathways for mammograms eligible for a second reading: the conventional second reading by an accredited radiologist (control arm) and the AI-assisted second reading (experimental arm) using the MammoScreen device. In the AI-assisted arm, the AI first reviews the mammogram, and only if it flags suspicion does a radiologist perform a second review. The final decision uses the more concerning result from either arm to determine if recall for further examination is needed. Participants will undergo screening mammograms with both reading processes applied. Researchers will compare diagnostic performance and economic impact between the two pathways, focusing on recall rates at the end of a 24-month inclusion period. Women will participate according to the breast cancer screening schedule and provide informed consent for study involvement.

Nasal obstruction (NO) affects about 30% of people and is a common reason for visits to ear, nose, and throat specialists. It is usually caused by inflammation, such as allergic rhinitis or chronic rhinosinusitis, but can also result from structural issues like septal deviation or enlarged turbinates. NO can greatly reduce quality of life and affect the sense of smell, and it can contribute to conditions like asthma and sleep apnea. Various questionnaires are used to assess the impact of NO on patients' well-being. This research evaluates anterior active rhinomanometry (AAR), a non-invasive test measuring nasal airway blockage, to see if it can reliably confirm when surgery is needed for nasal obstruction. AAR uses sensors to measure nasal pressure while breathing, performed without nasal decongestants. The study focuses on patients undergoing septoplasty, turbinoplasty, or rhinoplasty based on clinical exams and imaging. AAR results are compared with clinical and imaging findings to assess its usefulness as an independent surgical decision tool. Participants will have preoperative AAR testing, and data from questionnaires and clinical exams will be collected. Researchers will measure the reliability of AAR in identifying nasal obstruction that requires surgery on the day of surgery. The goal is to determine if AAR alone can guide surgical decisions, improving diagnosis and treatment planning for patients with nasal obstruction.