Embrun

Researchers are evaluating the impact of a brief motivational intervention BMI delivered by pharmacists to help reduce the use of benzodiazepines and related drugs BZDZ in adults who have been taking these medications long-term at least 6 months. The study aims to see if this intervention can lower the daily dose of these drugs after 6 months without causing worsening of anxiety or sleep disorders, compared to usual pharmacy dispensing practices. This research takes place in the context of increasing prescriptions and concerns about prolonged use of BZDZ, which carry risks and potential adverse effects. Participants will either receive the BMI, which involves identification and a motivational approach that uses patients psychosocial skills and supporting tools to reduce BZDZ use, or continue with the standard practice of dispensing these medications in pharmacies. The intervention targets adults with chronic use of BZDZ, aiming for a practical and scalable method that pharmacists can apply during routine care. The study is randomized and does not use blinding. During the study, participants will be monitored over 6 and 12 months to assess changes in daily BZDZ doses, complete cessation rates, anxiety, depressive symptoms, insomnia severity, misuse, and any adverse events. Questionnaires and clinical evaluations will be used to measure outcomes at several points, including 3, 6, 9, and 12 months. The goal is to understand both the reduction in drug use and the clinical effects on patients symptoms and safety throughout the follow-up period.

Researchers are evaluating a 4-week video-based education program to improve urinary continence in women with urinary incontinence who are referred for pelvic floor rehabilitation. This study aims to determine if watching structured videos reduces symptoms before starting pelvic floor muscle strengthening compared to receiving similar information in a paper document. The trial is led by Poitiers University Hospital and includes women 18 years or older with urinary incontinence. Participants will either watch the video-based program consisting of four weekly 20-minute workshops covering pelvic floor anatomy, urinary and digestive tract physiology, and urinary incontinence causes and prevention, or receive a paper information document with the same content. After this initial 4-week period, all participants undergo pelvic floor rehabilitation sessions as usual. The study compares outcomes between the video group and the paper group. Throughout the trial, participants complete urinary incontinence questionnaires after the education period and following each rehabilitation session, with monitoring continuing for up to 2 years. Researchers assess urinary incontinence severity, quality of life, pelvic floor and sexual symptoms, patient-perceived improvement, and physical activity changes. The primary outcome is the urinary incontinence score comparison between groups five weeks after inclusion. Long-term follow-up at 12 and 24 months evaluates lasting effects of the education and rehabilitation.