Fontainebleau

Researchers are evaluating the impact of vaccine funding provided by the National Health Insurance on vaccination coverage among patients targeted by current vaccination recommendations. The study focuses on patients seen in outpatient consultations within four healthcare institutions in the Ile-de-France region in France. The project aims to determine if dedicated vaccine funding can improve vaccination rates for vulnerable patients at risk of infections, such as pregnant women for pertussis and eligible patients for pneumococcal vaccination. The study involves several groups including women in the immediate postpartum period, patients eligible for pneumococcal vaccination with specific health coverage, and healthcare providers involved in vaccination efforts. Questionnaires will be used to collect information from patients and healthcare providers. The study will assess vaccination coverage for pertussis and pneumococcal infections at 3 and 18 months, along with evaluating socio-economic factors, changes in healthcare professional practices, and improvements in communication about vaccination status using digital tools. Participants will be monitored through outpatient consultation records and questionnaires. Researchers will measure the number of vaccinated individuals, factors influencing vaccination, and the frequency of vaccination offers and administration by healthcare providers. The study will also observe changes in documentation practices to enhance communication between institutions and primary care. The research is expected to run until July 2027, with a focus on improving vaccine reimbursement and coverage policies based on findings.

The UroCCR project is a national research network and registry focused on kidney cancer, designed to tackle the complexities of managing renal cell carcinoma. It collects detailed real-world data from over 21,000 cases across 58 centers in France, combining clinical, imaging, biological, and patient-reported information. This comprehensive dataset supports multiple research areas, including translational studies, clinical evaluation, and social sciences, with strong governance and national and international recognition. Participants in UroCCR are adult patients diagnosed with kidney cancer. The registry collects information on different treatment approaches, including radical nephrectomy and partial nephrectomy, with follow-up assessments scheduled at 3 months, 6 months, 12 months, then yearly for 5 years and every 2 years up to 10 years. The project also integrates digital tools and biobanking, enabling detailed study of treatment outcomes and tumor progression. During the study, participants contribute data through clinical evaluations, imaging, biological samples, and patient-reported outcomes. Researchers monitor complications, renal function, tumor progression, and mortality rates related to different surgical treatments. The registry links with national health data to provide long-term follow-up and supports multiple ancillary studies. The study duration can extend up to 15 years, allowing for comprehensive analysis of kidney cancer management and outcomes.