Mont Saint Aignan

This research aims to describe how patients aged 18 years or older with moderate to severe atopic dermatitis AD are managed with systemic therapy. It focuses on patients eligible for or currently receiving systemic treatments, following their care under real-world conditions. The study involves French dermatologists experienced in AD management, whether practicing in hospitals or private offices. Treatment decisions are made independently by the physicians and not influenced by the study enrollment. Participants will receive systemic treatments for AD prescribed by their doctors as part of routine care, with no investigational drugs involved. Information will be collected during regular visits according to usual clinical practice. The study will follow patients for one year, tracking their treatments and management without altering standard care. During the year, patients will be assessed at baseline, 6 months, and 12 months. Researchers will collect data on previous and current treatments, treatment adherence, changes in disease severity, itch, sleep disturbance, skin pain, quality of life, psychological health, work absences, and hospitalizations related to AD. This comprehensive follow-up aims to better understand how systemic therapies are used and their impact on patients in everyday clinical settings.

This research aims to assess the prevalence and changes over time of medico-psychological characteristics in children and adolescents placed full-time in child protective services structures in specific regions. The study focuses on how these characteristics evolve during the first two years following placement, considering different age groups. It investigates various behavioral and developmental conditions including psychiatric disorders as classified by DSM 5. Participants will undergo a series of assessments including a first interview with a psychologist shortly after placement, where cognitive tests, psychiatric classifications, and psychological evaluations are conducted. Follow-up assessments occur at one year M12 and two years M24 after inclusion, focusing on psychiatric and psychological status. The study uses questionnaires, scales, and cognitive tests as behavioral interventions. Throughout the study, researchers will collect detailed information on psychiatric disorders, cognitive abilities, attachment disorders, emotional and behavioral regulation, hallucinations, mentalization capacity, eating disorders, substance use, adverse life events, care pathways, coping strategies, depressive symptoms, and global functioning at the start and follow-ups. Participation involves structured evaluations at three time points over two years, helping understand developmental trajectories and adaptive methods in this vulnerable population.