Saint Amand Les Eaux

Gambling disorder (GD) is recognized as an addictive disorder characterized by craving, which can lead to relapse. This research evaluates the effectiveness of Virtual Reality Exposure Therapy (VRET) combined with Cognitive-Behavioral Therapy (CBT) compared to imaginal exposure therapy combined with CBT in treating GD. The study is a multicenter, randomized, controlled, non-inferiority clinical trial aiming to show that VRET is not less effective than imaginal exposure therapy in reducing GD symptoms. Participants will receive 12 treatment sessions, with 6 sessions focused on CBT and either 6 sessions of VRET or imaginal exposure therapy targeting gambling cues. VRET uses a virtual gambling environment to expose patients to triggers in a controlled way, while imaginal exposure involves mentally confronting gambling cues. Both therapies aim to reduce craving and gambling behaviors. During the study, researchers will assess changes in gambling severity using the South Oaks Gambling Screen (SOGS) at baseline and after treatment. They will also evaluate gambling behavior, craving, gambling-related thoughts, anxiety, depression, and treatment quality up to 12 months post-treatment. Participants will be monitored for adherence and outcomes throughout the study period.