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Found 4 Actively Recruiting clinical trials

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Actively Recruiting

Neurological disorders like cerebral palsy can cause significant motor challenges that affect daily life, especially in children. This research evaluates the use of intensive, repetitive training focused on reach-to-grasp movements to improve hand function in children aged 4 to 17 years with such motor impairments. The study explores a new approach combining serious gaming with physical training to make repetitive therapy more engaging and effective. Participants will engage in a 4-week intervention involving three 40-minute sessions per week using a specialized serious game. This game includes software, a physical platform, and instrumented toys designed to encourage grasp-and-release and reach-to-grasp actions through repeated movements. The therapy aims to provide about 4 hours of gameplay, with sessions including specific tasks like the Box and Blocks Test and range of motion exercises. Children will first complete baseline assessments measuring manual dexterity and wrist movement, along with the Assisting Hand Assessment. After the intervention, these tests will be repeated, and a follow-up evaluation will occur two months later to measure lasting effects. Researchers will track improvements using the Box and Blocks Test, active wrist range of motion, and the Assisting Hand Assessment to understand the therapys impact.

Age: 4Years - 17YearsAll GendersPhase Not Applicable
2 locations
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Actively Recruiting

Cerebral palsy is the most common motor disability in children, often causing significant challenges in upper limb use that affect independence and quality of life. Researchers are evaluating an intensive rehabilitation program combining Constraint-Induced Movement Therapy CIMT and Bimanual Intensive Therapy BIT to improve manual abilities in children with cerebral palsy. This study aims to assess the benefits of the HabilHand program and help optimize rehabilitation approaches for this population. The program lasts 10 days over a 2-week period and uses tailored therapy based on the childs age and care setting. Children aged 3 to 8 years receive about 60 hours of combined CIMT and BIT therapy in a day-hospital setting, while adolescents aged 9 to 17 years receive about 80 hours either as day-hospital or inpatient care. Each day includes two individual and three group sessions with functional and playful motor tasks that progressively increase in difficulty. Participants will undergo various assessments including the Assisting Hand Assessment and Both Hands Assessment at 3 months after the program. Additional evaluations such as the Melbourne Assessment 2, Canadian Occupational Performance Measure, and Gross Motor Function Measure will also be conducted at 3 months. The study monitors improvements in hand use and gross motor function, with safety and participation tracked throughout the process. The trial is sponsored by Fondation Ellen Poidatz and runs until December 2030.

Age: 3Years - 17YearsAll GendersPhase Not Applicable
1 location
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Actively Recruiting

Healthy Volunteer

Researchers are studying children with cerebral palsy CP, a group of movement and posture disorders caused by brain damage during fetal development or the first year of life. This research evaluates a new method using dynamometers to measure passive stiffness and spasticity in joints, aiming to improve the accuracy and reliability of these assessments compared to traditional clinical exams, which can be subjective and vary by examiner. The study uses a handheld dynamometer to perform passive stretch tests on the main lower limb joints of both children with CP and healthy children aged 7 to 18 years. Two evaluators conduct repeated measurements to assess the consistency and reliability of this new protocol. The study includes children classified within levels I to III of the Global Motor Function Classification System and requires their ability to follow simple instructions. Participants will undergo repeated passive joint assessments by two different evaluators to measure intra- and inter-rater reliability. Researchers will collect data on passive stiffness, model deviation, electromyography activity, and joint kinematics over a two-year period. The study monitors participants responses to these assessments while ensuring voluntary participation and parental consent, with a total involvement lasting up to two years.

Age: 7Years - 18YearsAll GendersPhase Not Applicable
1 location
U

Actively Recruiting

Cerebral palsy CP is a group of movement and posture disorders caused by brain damage during fetal development or early infancy, affecting activities like walking. This trial evaluates the impact of gait rehabilitation using a serious game in augmented reality AR called ARRoW-CP compared to traditional treadmill training. The study aims to improve motor learning and motivation in children and adolescents with CP after surgery, exploring effects on walking and functional abilities. Participants are children aged 10 to 17 years with CP who have undergone multisite lower limb surgery. They are randomly assigned to one of two groups a control group receiving classic rehabilitation plus treadmill gait training 3 times per week for 4 weeks, and a test group receiving the same rehabilitation plus overground ARRoW-CP gait training with an AR headset at the same frequency. The ARRoW-CP game provides real-time and delayed feedback on gait performance during walking sprints. During the study, participants undergo various tests including a 6-minute walking test, muscle power sprint test, shuttle run tests adapted for CP, and complete a motivation and satisfaction questionnaire. Researchers monitor gait parameters, functional abilities, motivation, adherence, and satisfaction. The total study duration includes baseline and follow-up assessments up to one year after inclusion to evaluate lasting effects.

Age: 10Years - 18YearsAll GendersPhase Not Applicable
1 location