Sainte Foy Les Lyon

Researchers are evaluating a remotely supervised online cognitive stimulation program compared to an unsupervised online cognitive exercise program to reduce cognitive complaints in patients treated for localized breast cancer after adjuvant chemotherapy. This study aims to understand if supervision by a neuropsychologist improves the effectiveness of cognitive interventions. Prior studies showed benefits from online programs, and this research explores the added value of personalized support and education during the intervention. The trial includes two groups one receiving a 12-week program with three 20-minute online cognitive sessions weekly plus a 30-minute weekly remote supervision session by a neuropsychologist, and a control group with access to the same online cognitive exercises without supervision. The exercises target up to 12 cognitive areas such as attention, memory, executive functions, and processing speed using the PRESCO program from the HAPPYNeuron-Pro software. Participants will be monitored over 12 weeks, with researchers assessing changes in perceived cognitive impairment using the Functional Assessment of Cancer Therapy-Cognitive Function FACT-Cog questionnaire. The primary outcome is the average change in the Perceived Cognitive Impairment subscale after 12 weeks. The study also evaluates adherence to the program and benefits on objective cognitive impairment. The study is randomized and includes adult female patients who have received chemotherapy and are undergoing radiotherapy.