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Found 2 Actively Recruiting clinical trials
Actively Recruiting
Minimally invasive surgery has greatly changed surgical practices since the 1980s, especially in urology where laparoscopy and robot-assisted surgery have advanced treatment of conditions like prostate cancer. In France and other countries, robotic surgery became widespread without strong studies confirming its benefits or guidelines on quality and access. This trial aims to carefully evaluate robot-assisted prostate removal compared to traditional laparoscopic and open surgery techniques to provide clear evidence for patients and healthcare decision-makers. Participants will undergo radical prostatectomy using one of three approaches: robot-assisted laparoscopy, conventional laparoscopy, or open surgery (laparotomy). Urinary and erectile functions will be assessed before and after surgery to compare outcomes across the three groups. This large prospective study is conducted at multiple centers to gather reliable data on the benefits and impacts of each surgical method. During the study, patients will be evaluated for urinary function using the EPIC 50 score 45 days after surgery. Researchers will also assess erectile and urinary functions before and after the prostatectomy. The study focuses on understanding how each surgical technique affects recovery and function, helping to inform patients and health authorities about the real advantages of robot-assisted surgery. Participants must be hospitalized for planned radical prostatectomy and will be monitored throughout their treatment and recovery.
Actively Recruiting
Researchers are evaluating the safety and quality of outpatient care compared to conventional hospital care for patients with acute uncomplicated appendicitis who undergo laparoscopic appendectomy. The study focuses on whether same-day discharge is as safe and effective as staying overnight in the hospital. This approach aims to improve patient satisfaction, reduce hospital stays, lower healthcare costs, and limit exposure risks during situations like the COVID-19 pandemic. The trial compares two treatments: ambulatory appendectomy, where the surgery is done in an outpatient unit and patients leave the hospital the same day, and conventional appendectomy, where patients stay overnight under observation after surgery in a digestive surgery department. Patients included are those with confirmed uncomplicated appendicitis and meet specific health and monitoring criteria, such as having a relative available for monitoring after discharge and living close to a hospital. Participants will be followed for 30 days after surgery to monitor overall safety and recovery. Researchers will assess complications, health status, and any morbi-mortality events during this period. The study includes careful screening before surgery, ongoing safety monitoring, and uses imaging and laboratory tests to confirm eligibility and health status. The total participation period covers the surgery day and 30 days of postoperative follow-up.