Tosse

Researchers are evaluating the effectiveness of a combined physical therapy and yoga program with patient education to reduce osteoarticular and musculoskeletal pain caused by hormone therapy in women treated for breast cancer. This study addresses the significant impact of such pain on quality of life and treatment adherence, exploring whether adding a therapeutic education program in postural yoga can help patients manage their pain and improve self-efficacy. The study also aims to analyze changes in inflammation-related cytokines before and after treatment to understand yoga's potential biological effects. Participants in the study are divided into two groups: one group receives a physical therapy-yoga educational program involving daily 15-minute yoga sessions at home using a guide and audio instructions for 12 weeks, plus one 90-minute weekly yoga-therapeutic education session led by a trained physical therapist during the first 6 weeks. The other group serves as a control and does not receive any yoga sessions or therapeutic education. This randomized, open-label, controlled trial builds on a promising pilot study and is conducted across multiple centers. Throughout the 12-week study period, participants' pain levels and quality of life are monitored, along with assessments of fatigue and self-efficacy. Researchers will evaluate the primary outcome of pain reduction and examine biological markers by measuring cytokine levels at the start and end of the program. Patients' adherence to the home yoga practice is supported by educational materials, and safety and treatment effects are carefully observed to understand the benefits and feasibility of this approach in breast cancer patients experiencing hormone therapy-related pain.