Kourou

Researchers are investigating kidney cancer through the UroCCR project, a national registry and research network in France dedicated to renal cell carcinoma (RCC). This platform collects detailed clinical, imaging, biological, and patient-reported data on kidney cancer from over 21,000 cases across 58 centers. The study aims to improve understanding of RCC management by integrating multidisciplinary care data, biological samples, and linking with national health datasets to support translational research, clinical evaluation, and social science studies. The study compares two surgical treatments for kidney cancer: radical nephrectomy and partial nephrectomy, with the choice of surgery made according to surgeon judgment. It follows patients over long periods, monitoring outcomes and complications after surgery. This national collaboration includes digital tools like perioperative monitoring and machine learning models to predict recurrence and survival. The network also supports ancillary studies, including retrospective and prospective clinical trials, to advance personalized treatment strategies. Participants provide comprehensive data on their clinical status, treatments, and quality of life. Researchers assess complications at multiple time points: 3, 6, and 12 months post-surgery, then yearly for 5 years, and every 2 years for up to 10 years. The study evaluates real-world outcomes in kidney cancer care, linking clinical information with biological samples and national health data, while ensuring standardized procedures, ethical oversight, and high data quality through robust governance.