Schwelm

Researchers are studying the impact and burden of three skin conditions moderate or severe alopecia areata, non-segmental vitiligo, and moderate to severe hidradenitis suppurativa. The study includes adolescents and adults and aims to understand how these conditions affect quality of life and daily functioning in a large global population. This is an observational study where participants with each condition will have a single visit for data collection following routine clinical practice. No experimental treatments are given instead, the study gathers information during this one visit to assess disease characteristics and impact. During the visit, participants will complete questionnaires and clinical assessments specific to their condition. These include tools measuring symptom impact, hair loss severity, skin depigmentation, and quality of life related to each disease. This helps researchers better understand the real-world burden of these conditions. Participation involves only this one visit, with no long-term follow-up or additional procedures.

Plaque psoriasis is a chronic inflammatory disease characterized by thick, red and white scaly patches on the skin. This observational study evaluates the change in quality of life for adults with moderate to severe plaque psoriasis who are treated with risankizumab in real-world clinical settings. The study will enroll about 700 participants worldwide who are prescribed risankizumab according to local medical guidelines. Participants will receive risankizumab as prescribed by their doctors following routine clinical practice and the local label. No additional treatments or procedures are imposed by the study. Participants will be followed for up to 2.5 years to observe their treatment experience and quality of life outcomes. During the study, participants will attend regular visits at hospitals or clinics as part of their usual care. Researchers will measure outcomes such as the Dermatology Life Quality Index score at 12 months to assess the impact of risankizumab on quality of life. The study does not add extra burdens beyond routine clinical visits and will monitor participants until study completion in March 2028.