Balligavi

Researchers are evaluating the pharmacodynamic bioequivalence of two albuterol sulfate metered dose inhalers MDIs in adults with stable mild asthma. This study compares a test formulation with a reference formulation using a methacholine bronchoprovocation challenge to measure bronchodilation potency. The study uses a crossover design to assess how well the inhalers inhibit airway responsiveness as indicated by the concentration of methacholine needed to reduce lung function by 20%.