Mahbubnagar

This research investigates bone regeneration in patients with intrabony defects by comparing the effects of bentonite clay gel combined with hydroxyapatite to hydroxyapatite alone. The study aims to evaluate the healing potential of bentonite gel, which may support cell infiltration and proliferation, in promoting bone repair. Participants will undergo flap surgery where either bentonite clay gel with hydroxyapatite or hydroxyapatite alone will be applied to the defect site. Those receiving the test treatment will have the bentonite gel added to the bone defect, while the control group will receive only hydroxyapatite. During the study, participants will have evaluations at baseline, 3 months, and 6 months. These assessments include radiographic imaging (RVG), measuring probing depth, and clinical attachment level to monitor bone healing and periodontal health. The study tracks these clinical outcomes to determine the effectiveness of the treatments over time.

This research aims to evaluate the clinical effect of hyaluronic acid gel in augmenting the papilla, which is the small gum tissue between teeth. The study focuses on patients with gingival destruction, specifically those who have interdental papilla recession in the front teeth of the upper or lower jaws. The goal is to assess how well hyaluronic acid hydrogel can improve this condition compared to a placebo treatment. Participants will be divided into two groups: one group will receive injections of hyaluronic acid hydrogel directly into the areas of papillary deficiency using a syringe, and the control group will receive injections of a saline placebo gel in the same manner. The hyaluronic acid gel is known for its role in tissue repair and wound healing by promoting cell growth and interaction with growth factors, as well as its space-filling properties due to its moisture-retaining nature. During the study, researchers will monitor the papilla augmentation from the start of treatment to six months afterward. Participants will undergo evaluations to measure changes in the gum tissue between teeth, and the study will ensure participants have good oral hygiene and no active gum diseases. Safety and effectiveness will be carefully tracked throughout the duration of the study to understand the potential benefits of hyaluronic acid gel for papilla augmentation.