Duhok

Anterior cruciate ligament (ACL) tears are common knee injuries often caused by sports or daily activities. Females have a higher risk of ACL tears compared to males in similar sports. Surgery to reconstruct the ACL is needed for those with frequent knee instability or high physical demands to prevent early knee damage. Postoperative infections after ACL reconstruction occur in a small percentage of cases and can lead to pain, stiffness, and cartilage damage. Some studies suggest soaking the ACL graft in vancomycin before surgery may reduce infection risk, but no randomized controlled trials have confirmed this yet. This trial compares two approaches in ACL reconstruction surgery to prevent infection: one group receives parenteral antibiotic injections alone, and the other group receives the same antibiotics plus an ACL graft soaked in vancomycin for 20 minutes before implantation. The parenteral antibiotic ceftriaxone is given in three doses around the time of surgery. The study uses a randomized controlled design with equal allocation to each group. Participants aged 20 to 45 years with ACL injury needing reconstruction will be monitored for infection signs for up to six months after surgery. Researchers will collect data on infection occurrence to compare the effectiveness of the treatments. The study will be conducted at Azadi Teaching Hospital in Iraq and includes detailed statistical analysis to evaluate the results. The trial aims to enroll at least 288 participants to detect meaningful differences between the two treatment methods.