Castlebar

Pilonidal sinus disease (PSD) is a chronic skin condition that causes infection and pain in the natal cleft area, often affecting young adults. This research compares two approaches to wound care after surgical removal of chronic PSD to see which leads to faster healing and better patient-reported outcomes. The study is a single-blinded, multicentre, prospective randomized controlled trial focused on improving recovery after surgery for PSD. The trial compares negative pressure wound therapy (NPWT), where a special dressing applies suction to the wound, with standard open wound care after surgery to remove the pilonidal sinus. Participants receive either NPWT applied to their wound post-surgery or standard open wound care without primary closure. The study evaluates how these treatments affect the time it takes for the wound to fully heal following surgery. Participants are monitored for wound healing and patient-reported outcomes over six months after surgery. Researchers will assess the time to complete wound healing and track recovery progress through questionnaires and clinical evaluations. The study aims to provide evidence on the best post-operative wound care method to reduce complications and improve quality of life for patients with PSD.

Researchers are evaluating if Negative Pressure Wound Therapy (NPWT) dressings can reduce surgical site infections, post-surgical complications, and improve scar appearance compared to standard wound dressings in patients undergoing abdominal surgery through a midline laparotomy. The study addresses the significant impact of wound complications after abdominal surgery, which can delay recovery, increase hospital stay, and raise healthcare costs. Limited data exists on the use of NPWT for laparotomy incisions, so this trial aims to provide evidence for its effectiveness and cost implications in both acute and elective surgical settings. The study compares two groups: one receiving NPWT dressings applied to the surgical wound after laparotomy and the other receiving standard wound dressings. NPWT dressings work by removing and absorbing fluid leaking from the wound, potentially improving healing and scar outcomes. Both treatments are applied after the surgical procedure. The trial includes evaluation periods at 1, 3, and 6 months after surgery to monitor wound healing and infection rates. Participants will be involved in follow-up assessments including monitoring for surgical site infections at multiple time points after surgery. Researchers will also collect data on wound healing, scar appearance, and patient quality of life through questionnaires. The study will include a cost analysis to understand the economic impact of using NPWT dressings. Overall participation covers the immediate post-operative period and extends through 6 months of follow-up to capture both short- and longer-term outcomes.