Search Bar & Filters
Found 1 Actively Recruiting clinical trials
Actively Recruiting
Researchers are studying how best to treat trauma patients with low blood pressure (hypotension) before they reach the hospital, focusing on how different prehospital care methods affect recovery and survival in the hospital. The study addresses gaps in evidence about treatments like prehospital blood transfusions and resuscitative endovascular balloon occlusion of the aorta (REBOA). It also examines the variability in emergency medical services across Italy, especially in helicopter emergency medical services (HEMS), and how these differences might impact patient outcomes. Participants will receive various treatments during prehospital care, including drugs such as antifibrinolytics, analgesics, sedatives, and neuromuscular blockers; devices like REBOA and extended focused assessment sonography for trauma (eFAST); blood transfusions; and different management strategies like "stay and play" versus "scoop and run." Each patient’s demographic information, trauma type, injury severity, and therapies used will be recorded for analysis. Throughout the study, researchers will collect data on hospital outcomes such as the need for blood transfusions, blood gas parameters, length of hospital and ICU stays, use of invasive ventilation and kidney support therapies, recovery progress, and mortality within 30 days. This comprehensive monitoring aims to identify factors during prehospital care that relate to survival and recovery after trauma, with participant involvement lasting through hospitalization and follow-up for 30-day mortality.