Toyooka

Researchers are evaluating the effects of hypothermia versus normothermia on patients who have experienced out-of-hospital cardiac arrest and received extracorporeal cardiopulmonary resuscitation (ECPR). This cluster randomized trial, called the SAVE-J NEUROTHERM trial, aims to compare mortality risk, neurological outcomes, and adverse events between these temperature control strategies. The study addresses the ongoing debate about optimal temperature management after cardiac arrest, especially in patients treated with ECPR using extracorporeal membrane oxygenation (ECMO).