Kalifabougou

Researchers are gathering detailed information on pregnancy rates, outcomes, and infant health in Kalifabougou, Mali, to support future clinical trials testing monoclonal antibodies for preventing malaria during pregnancy. This observational registry focuses on women of childbearing age and their infants to better understand pregnancy-related malaria and health issues. The study has two main parts. First, the Community Census Cohort identifies and follows women of childbearing age for up to three years to detect pregnancies at any stage. Once pregnancy is detected, women may join the Health Facility Cohort, where data are collected prospectively during antenatal care visits. Pregnant women in this group will be followed through delivery and up to 12 months after birth, with their infants followed for the first year of life. Participants will provide information on early pregnancy events, pregnancy and postpartum complications, malaria infections, use of malaria prevention tools, birth outcomes, and infant health. Researchers will track pregnancy numbers, malaria cases, anemia, maternal and infant deaths, birth complications, and vaccine timing. The study aims to provide a comprehensive view of pregnancy and infant health related to malaria in this community, with monitoring continuing through pregnancy and the infants first year.