Brumunddal

This observational study focuses on parastomal hernia repair using endoscopic methods. It evaluates laparoscopic and robotic extraperitoneal mesh repair techniques that include transversus abdominis release TAR and mesh reinforcement following the Sugarbaker principle. The study aims to assess these surgical approaches and their outcomes over time. The repair involves an endoscopic trans-abdominal preperitoneal plasty TAPP method placing mesh extraabdominally, anterior to the transversalis fascia. Both laparoscopic and robotic procedures are used, with additional repair of any midline hernias through an enhanced-view Rives-Stoppa technique. This approach is studied for safety and effectiveness in reinforcing hernia repair. Participants will be monitored for adverse events within one month after the procedure, with further follow-up over two years to observe late complications and hernia recurrence. The study collects data through clinical evaluations during this period. Participation duration varies with follow-up assessments scheduled up to two years after surgery to ensure comprehensive monitoring of outcomes.

Researchers are evaluating a virtual reality VR technology designed to help people with substance use disorders and mental health conditions improve their social functioning. This multi-center, pragmatic randomized controlled trial RCT compares VR training to usual treatment in patients receiving long-term addiction therapy. The study aims to measure improvements in resilience, quality of life, practical and social functioning, social participation over six months, and assess the cost-effectiveness of VR training over twelve months. Participants assigned to the VR group will attend two VR sessions per week for five weeks, totaling ten sessions. During these sessions, they will experience various virtual city environments with increasing complexity, facing everyday social situations. Initial sessions include instructions on using the VR equipment and navigating scenarios, with some sessions involving observation and others allowing participants to select responses presented both visually and verbally. The control group will continue receiving standard addiction treatment, which includes individual and group therapies, physical exercise, and social activities led by healthcare professionals. Throughout the study, participants will be monitored for changes in health, disability, social and practical functioning, social participation, and resilience from enrollment until about six months. Cost-effectiveness will be evaluated up to twelve months. Assessments include questionnaires and clinical observations. The study runs until December 2026, with participants expected to attend regular VR sessions if assigned and continue their usual care during and after the trial.