Llano Bonito

Researchers are comparing two bowel preparation agents, Lactulose and Sodium Phosphate, to determine which is better for high-quality colonoscopies. This trial is conducted as a randomized, double-blind study involving patients scheduled for outpatient colonoscopy at hospitals in Mexico and Panama between April 1, 2025, and November 30, 2025. The study focuses on colonoscopy quality, patient tolerance, satisfaction, and changes in electrolyte levels. Participants will be randomly assigned to receive either Lactulose or Sodium Phosphate as their bowel preparation on the day they receive their colonoscopy appointment. Both agents are given orally before the procedure. The study excludes patients undergoing emergency or therapeutic colonoscopies and those with specific medical conditions or pregnancy. Data collected include bowel preparation effects and colonoscopy findings, analyzed using statistical software. During the study, participants will undergo assessments such as blood tests to monitor electrolyte changes, evaluation of gastrointestinal side effects, and measures of bowel preparation quality using the Boston Bowel Preparation Scale. Researchers will also assess palatability and adenoma detection rates. Participant data will be securely stored and analyzed to draw conclusions on the best preparation method. The total study period runs from April to November 2025.