Janki

Researchers are evaluating the growth, gastrointestinal tolerance, quality of life, and acceptability of a new hydrolyzed rice protein-based formula in infants with cow's milk protein allergy (CMPA). The study aims to show that infants fed with this test formula grow as well as those fed with a commercially available extensively hydrolyzed cow's milk formula. This is a randomized nutritional clinical study focusing on infants diagnosed with CMPA. Participants will receive either the test formula made from hydrolyzed rice protein or the control formula which is an extensively hydrolyzed cow's milk formula. The study compares these two feeding options to assess growth and tolerance. The infants will be fed according to the assigned formula while maintaining a strict cow's milk elimination diet throughout the study period. During the study, researchers will monitor infant growth by measuring the weight-for-age z-score up to 4 months after enrollment. They will also evaluate gastrointestinal tolerance, health-related quality of life, and formula acceptability. Parents or guardians will provide consent and participate in the study process. The study involves regular follow-ups to assess health and growth outcomes over the course of the 4-month period.