Sayanogorsk

Researchers are conducting an observational surveillance study to identify the genetic types of rickettsia bacteria causing rickettsioses in patients from various regions of Russia. The study focuses on patients with diagnosed or suspected tick-borne rickettsioses. It aims to link genetic information of the bacteria with patients' medical histories, disease progression, symptoms, and treatments to find clinical patterns specific to different causative agents. The study is non-interventional and has received ethical committee approval. No changes are made to patients' routine treatment or diagnostic procedures during the study. Biological samples such as blood, plasma, buffy coat, serum, or eschar swabs collected during standard diagnostics are used for genetic analysis of the rickettsia species. These residual diagnostic samples are collected only after patients or their legal representatives give written informed consent. Physicians complete individual case report forms to record relevant medical information for each participant. Participants provide informed consent, and their medical history, symptoms, disease course, and treatments are recorded. The genetic typing of rickettsia bacteria is performed within up to 4 weeks after sample collection. The study monitors these genetic findings alongside clinical data to improve understanding of rickettsioses. There is no intervention or alteration in patient care, and the study respects current medical standards throughout its observation period.